Baycox (toltrazuril) 5% Oral Suspension

Baycox^® is indicated for thetreatment of preclinical coccidiosis due to Isosporasuis in neonatal piglets, for the prevention of clinical signs ofcoccidiosis and reduction of coccidian shedding in lambs on farms with aconfirmed history of coccidiosis caused by Eimeriacrandallis and Eimeria ovinoidalis,and for the prevention of clinical signs of coccidiosis and reduction ofcoccidian shedding in calves on farms with a confirmed history of coccidiosiscaused by Eimeria bovis and Eimeria zuernii.

Baycox^® is not indicated for use in feedlot cattle.

Dosageand Administration: Piglets: Shake well before use.Weigh three representative litters at 3 days of age to determine anaverage piglet weight. The recommended dosage of toltrazuril is 20 mg per kgbody weight. This corresponds to a dose of 1 mL Baycox^® per 2.5 kg bodyweight.

Administer a single oral dose at 3 to 4 days of age.

Lambs: Shake well before use. Each animal should be treated witha single dose of 20 mg toltrazuril/kg body weight corresponding to 1 mL Baycox^® per 2.5 kg body weight. To obtain maximumbenefit, sheep should be treated in the prepatent period before the expectedonset of clinical signs. The prepatent period of Eimeriaovinoidalis is 12-15 days and the prepatent period of Eimeria crandalis is 15-20 days. Ifanimals are to be treated collectively rather than individually, they should begrouped according to their body weight and dosed accordingly, in order to avoidunder- or overdosing. In order to maximize effectiveness of Baycox^® in lambs it is important to time therapyaccording to individual farm management and lifecycle of the organism involved.

Calves: Shake well before use. Each animal should be treated witha single oral dose of 15 mg toltrazuril/kg body weight corresponding to 3mL Baycox^® per 10 kg body weight. To obtain maximumbenefit, calves should be treated in the prepatent period before the expectedonset of clinical signs. The prepatent period of Eimeriazuernii is 15-17 days and the prepatent period of Eimeria bovis is 18-21 days. If animalsare to be treated collectively rather than individually, they should be groupedaccording to their body weight and dosed accordingly, in order to avoid under-or overdosing. It is important to time therapy according to individual farmmanagement and lifecycle of the organism involved.

Cautions:

As with any antiparasiticide, frequent and repeated use ofantiprotozoals from the same class may lead to the development of resistance.

Warnings:Piglets: Treated swine must not be slaughtered for use in food forat least 70 days after the latest treatment with this drug. Do not use inpiglets intended to be used as suckling or barbecue pigs since they may bemarketed before 70 days after administration of this drug. Lambs: Treated sheep must not beslaughtered for use in food for at least 48 days after the latest treatmentwith this drug.

- Do not use in lactating sheep producing milk for humanconsumption.

Calves: Treated cattle must not be slaughtered for use in food forat least 63 days after the latest treatment with this drug.

- Do not use in calves to be processed for veal. A withdrawalperiod has not been established for this product in pre-ruminating calves.

- Do not use in lactating dairy cows producing milk for humanconsumption.

Avoid direct contact with skin by wearing rubber gloves whilehandling this drug. Dispose the unused drug in accordance with theProvincial/Municipal guidelines.

Keep out of reach of children